700016P

cholesterol sulfate

Avanti Research^™ - A Croda Brand 700016P

• Sinónimos: cholesterol sulfonate; cholesteryl sulfate; sodium cholesteryl sulfate; cholesteryl sulphate
• Fórmula empírica (notación de Hill): C₂₇H₄₅NaO₄S
• Número de CAS: 2864-50-8
• Peso molecular: 488.70
• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• descripción: cholesterol 3-sulfate (sodium salt)
• Ensayo: >99% (TLC)
• Formulario: powder
• envase: pkg of 1 × 1 g (700016P-1g); pkg of 1 × 25 mg (700016P-25mg); pkg of 1 × 500 mg (700016P-500mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 700016P
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].[S](=O)(=O)([O-])O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC=C2C1)C
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• Clave InChI: LMPVQXVJTZWENW-KPNWGBFJSA-M

Descripción

Descripción general

Cholesterol sulfate is synthesized by the sulfoconjugation of cholesterol in the presence of enzyme cholesterol sulfotransferase. It is present in brain, lungs, hair and skin tissues as well as cells including erythrocytes, platelets and spermatozoa.

Aplicación

Cholesterol sulfate has been used in micelle preparation and in surface plasmon resonance (SPR) studies.

Acciones bioquímicas o fisiológicas

Cholesterol sulfate is associated with atherosclerotic lesions and serves as a substrate for platelet adhesion. It stabilizes the spermatozoa membranes and erythrocytes. Cholesterol sulfate is involved in the keratinocyte differentiation and its levels are elevated in recessive X-linked ichthyosis. It serves as a ligand for retinoic acid-related orphan receptor α (RORα). Cholesterol sulfate regulates glucose metabolism and is a potential target for metabolic disorders. It is also a potential marker for human uterine cervical carcinoma tissue and prostate carcinoma.

Envase

20 mL Clear Glass Screw Cap Vial (700016P-1g)

20 mL Clear Glass Screw Cap Vial (700016P-500mg)

5 mL Amber Glass Screw Cap Vial (700016P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable