QBD10502

Azido-dPEG^®₄-acid

• Sinónimos: 15-Azido-4,7,10,13-tetraoxapentadecanoic acid, 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, Polyethylene glycol
• Fórmula empírica (notación de Hill): C₁₁H₂₁N₃O₆
• Número de CAS: 1257063-35-6
• Peso molecular: 291.30
• Número MDL: MFCD12406155
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 329823931
• NACRES: NA.22

Propiedades

• Análisis: >90%
• formulario: solid or viscous liquid
• idoneidad de la reacción: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• grupo funcional: azide; carboxylic acid
• arquitectura del polímero: shape: linear; functionality: heterobifunctional
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O
• InChI: 1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
• Clave InChI: BODPHGOBXPGJKO-UHFFFAOYSA-N

Descripción

Características y beneficios

The azido-dPEG^®₄ contains an azide function on one end of a single molecular weight dPEG^® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Información legal

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable