QBD10275

MAL-dPEG^®₈-acid

>95% (HPLC)

• Sinónimos: Carboxy-PEG-maleimide, Carboxy-PEG₈-maleimide, MAL-PEG₄₀₀-acid, MAL-PEG₈-COOH, MAL-PEG₈-acid
• Fórmula empírica (notación de Hill): C₂₆H₄₄N₂O₁₃
• Peso molecular: 592.63
• Número MDL: MFCD13184956
• Código UNSPSC: 12352106

Propiedades

• Análisis: >95% (HPLC)
• formulario: solid or viscous liquid
• idoneidad de la reacción: reaction type: Pegylations
• arquitectura del polímero: shape: linear; functionality: heterobifunctional
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Características y beneficios

MAL-dPEG₈-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions.

Información legal

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable