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Merck

909858

Sigma-Aldrich

Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 20,000, lactide:glycolide 50:50

Sinónimos:

COOH-PEG-PLGA, Carboxylic acid PEG-PLGA

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About This Item

Fórmula lineal:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2
Código UNSPSC:
12352106
NACRES:
NA.23

formulario

powder or chunks

cociente alimentación

lactide:glycolide 50:50

mol peso

PEG average Mn 5,000 (by NMR)
PLGA average Mn 20,000 (by NMR)

color

white to tan

temp. de almacenamiento

−20°C

Aplicación

Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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