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Merck

767549

Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 20,000, PEG average Mn 20,000 (n~450), acrylate, ≤1000 ppm MEHQ as inhibitor

Sinónimos:

PEG diacrylate, Polyethylene glycol

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About This Item

Código UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) diacrylate, average Mn 20,000, contains ≤1000 ppm MEHQ as inhibitor

formulario

solid

mol peso

PEG average Mn 20,000 (n~450)
average Mn 20,000

contiene

≤1000 ppm MEHQ as inhibitor

idoneidad de la reacción

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

mp

60-65 °C

Ω-final

acrylate

α-final

acrylate

arquitectura del polímero

shape: linear
functionality: homobifunctional

temp. de almacenamiento

−20°C

Descripción general

Poly(ethylene glycol) diacrylate (PGEDA) is used for synthesising highly cross-linked hydrogels which are used as biomaterials in tissue engineering. These hydrogels are formed using non-cytotoxic photo initiators. PEG hydrogels can be easily covalently linked to bioactive proteins and peptides which in turn promote specific cell activity either on the surface or within the hydrogel.

Aplicación

This homobifunctional PEG can be used in hydrogel applications; biocompatibilization; thiol-ene coupling; and other applications using cross-linked PEG networks.

Pictogramas

CorrosionExclamation mark

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Julia E Leslie-Barbick et al.
Biomaterials, 32(25), 5782-5789 (2011-05-27)
Microvascularization of tissue engineered constructs was achieved by utilizing a VEGF-mimicking peptide, QK, covalently bound to a poly(ethylene glycol) hydrogel matrix. The 15-amino acid peptide, developed by D'Andrea et al., was modified with a PEG-succinimidyl ester linker on the N-terminus
Pilnam Kim et al.
Lab on a chip, 6(11), 1432-1437 (2006-10-27)
We present a simple and widely applicable method to fabricate micro- and nanochannels comprised entirely of crosslinked polyethylene glycol (PEG) by using UV-assisted irreversible sealing to bond partially crosslinked PEG surfaces. The method developed here can be used to form
Won-Gun Koh et al.
Langmuir : the ACS journal of surfaces and colloids, 18(7), 2459-2462 (2002-06-29)
We present an easy and effective method for the encapsulation of cells inside PEG-based hydrogel microstructures fabricated using photolithography. High-density arrays of three-dimensional microstructures were created on substrates using this method. Mammalian cells were encapsulated in cylindrical hydrogel microstructures of
Ruohong Shi et al.
Small (Weinheim an der Bergstrasse, Germany), 16(37), e2002946-e2002946 (2020-08-11)
Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide-co-bis-acrylamide

Artículos

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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