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767344

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 20,000 (NMR), PDI ≤1.3

Sinónimos:

PDLA, PLA, polyDL-lactide

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About This Item

Código UNSPSC:
12162002
NACRES:
NA.23

formulario

crystals

mol peso

average Mn 20,000 (NMR)

marco temporal de la degradación

<6 months

mp

320-350 °C

PDI

≤1.3

temp. de almacenamiento

2-8°C

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Categorías relacionadas

Aplicación

Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H319

Clasificaciones de peligro

Eye Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Synthesis of Shape Amphiphiles Based on Functional Polyhedral Oligomeric Silsesquioxane End-Capped Poly(L-Lactide) with Diverse Head Surface Chemistry
Zhang W B, et al.
Macromolecules, 44(8), 2589-2596 (2011)
Poly(lactide)-block-Poly(HEMA) Block Copolymers: An Orthogonal One-Pot Combination of ROP and ATRP, Using a Bifunctional Initiator
Wolf F F, et al.
Macromolecules, 42(15), 5622-5628 (2009)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Artículos

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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