415057

Magnesium stearate

technical grade

• Sinónimos: Stearic acid magnesium salt
• Fórmula lineal: [CH₃(CH₂)₁₆CO₂]₂Mg
• Número de CAS: 557-04-0
• Peso molecular: 591.24
• Beilstein: 3919702
• Número CE: 209-150-3
• Número MDL: MFCD00036391
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24865972
• NACRES: NA.22

Propiedades

• grado: technical grade
• Nivel de calidad: 100
• Formulario: powder
• composición: palmitate salt, 25% ; stearate salt, 65%
• mp: 200 °C (lit.)
• cadena SMILES: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• Clave InChI: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Descripción

Descripción general

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Magnesium stearate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.

Aplicación

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves