302120

n-Butil-litio solution

2.0 M in cyclohexane

• Sinónimos: n-BuLi, Butil litio, Butil-litio solution, Litio-1-butanida
• Fórmula lineal: CH₃(CH₂)₃Li
• Número de CAS: 109-72-8
• Peso molecular: 64.06
• Beilstein: 1209227
• Número MDL: MFCD00009414
• Código UNSPSC: 12352103
• ID de la sustancia en PubChem: 24858234
• NACRES: NA.22

Propiedades

• Formulario: liquid
• Nivel de calidad: 200
• concentración: 2.0 M in cyclohexane
• bp: 80 °C
• densidad: 0.775 g/mL at 25 °C
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [Li]CCCC
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;
• Clave InChI: MZRVEZGGRBJDDB-UHFFFAOYSA-N

Descripción

Descripción general

n-Butyllithium (n-BuLi) is an organolithium reagent widely used as a strong base (superbase) in organic synthesis for the preparation of various chemical intermediates. It is also used as a reagent for lithium-halogen exchange and lithium-metal transmetalation reactions. n-BuLi is capable of lithiating carbon acids.

Aplicación

n-Butyllithium (2.0 M in cyclohexane) can be used as:      

• A polymerization initiator to synthesize polystyrenes by anionic polymerization of styrene.      
• A strong base in the diastereoselective alkylation reactions.
• A reagent to synthesize 2-benzoylpyrroles by reacting benzaldehydes with di(1H-pyrrol-1-yl)zirconium(IV) chloride complex.

Envase

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Información legal

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Información de seguridad

• Pictogramas: GHS02,GHS08,GHS05,GHS07,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H225,H260,H304,H314,H336,H410
• Consejos de prudencia: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• Órganos de actuación: Central nervous system
• Riesgos supl.: EUH014
• Código de clase de almacenamiento: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): -0.4 °F - closed cup
• Punto de inflamabilidad (°C): -18 °C - closed cup
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter