227439

Lawesson reagent

97%

• Sinónimos: 2,4-Bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphosphetane, 2,4-Bis-(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide, 4-Methoxyphenylthiophosphoric cyclic di(thioanhydride), LR
• Fórmula empírica (notación de Hill): C₁₄H₁₄O₂P₂S₄
• Número de CAS: 19172-47-5
• Peso molecular: 404.47
• Beilstein: 1024888
• Número MDL: MFCD00005171
• Código UNSPSC: 12352005
• ID de la sustancia en PubChem: 24853631
• NACRES: NA.22

Propiedades

• Nivel de calidad: 100
• Análisis: 97%
• formulario: powder
• mp: 228-230 °C (lit.)
• cadena SMILES: COc1ccc(cc1)P2(=S)SP(=S)(S2)c3ccc(OC)cc3
• InChI: 1S/C14H14O2P2S4/c1-15-11-3-7-13(8-4-11)17(19)21-18(20,22-17)14-9-5-12(16-2)6-10-14/h3-10H,1-2H3
• Clave InChI: CFHGBZLNZZVTAY-UHFFFAOYSA-N

Descripción

Descripción general

Lawesson′s reagent is generally used as a thiation agent in organic synthesis for the conversion of oxygen functionalities into their thio analogs. It facilitates the conversion of the carbonyl group to thiocarbonyl group as well as carbon-oxygen single bond into a carbon-sulfur single bond.

Aplicación

Lawesson reagent can be used as a reagent to synthesize:

• Oxthiaphosphinine-3-sulfide derivatives by the reaction with Mannich bases of β-naphthol and 8-hydroxyquinoline.
• 1,3,5,2-Trithiaphosphinane-2-sulfide derivatives by reacting with benzaldehyde in the presence of trialkyl phosphite.
• 2,4,6-Triphenyl-1,3,5-trithiane from benzaldehyde and ethyl acrylate.
• 9-Benzanthronethione by thionation of 9-benzanthone oxime.
• 1,2,4-Trithiolane from 2,2,4,4-tetramethyl-3-thioxocyclobutanone S-oxide.
• Sulfur derivatives of triterpenic oxo compounds.
• Tropothione in situ at room temperature and to trap it with dieneophiles.

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Danger
• Frases de peligro: H261
• Consejos de prudencia: P231 + P232 - P422
• Clasificaciones de peligro: Water-react 2
• Riesgos supl.: EUH029
• Código de clase de almacenamiento: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable