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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Sinónimos:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
western blot
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Flecainide acetate salt, ,
Especie
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Lamotrigine, ≥98%, powder,
Especie
rat, human
Cocaine free base, ,
Especie
mouse, rat, human
Carbamazepine, powder,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SCN5A,
Especie
human