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Merck

PTPRN

protein tyrosine phosphatase, receptor type, N

Sinónimos:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Especie:
ID UniProtKB:
ID del gen:
  • Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
  • Mouse(19275) protein tyrosine phosphatase, receptor type, N
  • Rat(116660) protein tyrosine phosphatase, receptor type, N
  • domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
  • dog(478921) protein tyrosine phosphatase, receptor type, N
  • cow(286810) protein tyrosine phosphatase, receptor type, N
  • sheep(101113312) protein tyrosine phosphatase, receptor type, N
  • Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
  • naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N
  • domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-IA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-IA-2, clone 76F Antibody, clone 76F, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-ICA 512/RESP18 Antibody, clone 1348-D29-1, ,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

Proteins

Referencia del producto
Descripción
Especie
PTPIA2 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PTPRN,
Especie
human
MISSION® esiRNA, targeting mouse Ptprn,
Especie
mouse