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Merck

PADI1

peptidyl arginine deiminase, type I

Sinónimos:
HPAD10, PAD1, PDI, PDI1
Especie:
ID UniProtKB:
ID del gen:
  • Human(29943) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18599) peptidyl arginine deiminase, type I
  • Rat(54282) peptidyl arginine deiminase, type I
  • sheep(101108201) peptidyl arginine deiminase, type I
  • domestic guinea pig(100728246) peptidyl arginine deiminase, type I
  • naked mole-rat(101722077) peptidyl arginine deiminase, type I
  • chicken(428171) peptidyl arginine deiminase, type I
  • cow(618224) peptidyl arginine deiminase, type I
  • Horse(100049961) peptidyl arginine deiminase, type I
  • domestic cat(101085557) peptidyl arginine deiminase, type I
  • dog(608443) peptidyl arginine deiminase, type I

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PADI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Proteins

Referencia del producto
Descripción
Especie
PADI-1 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Especie
human
PAD1, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
PAD Cocktail, Active, recombinant,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PADI1,
Especie
human