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Merck

MAN1B1

mannosidase, alpha, class 1B, member 1

Sinónimos:
ERMAN1, MANA-ER, MRT15
Especie:
ID UniProtKB:
ID del gen:
  • Human(11253) Summary: This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
  • Mouse(227619) mannosidase, alpha, class 1B, member 1
  • Rat(499751) mannosidase, alpha, class 1B, member 1
  • domestic guinea pig(100715996) mannosidase, alpha, class 1B, member 1
  • naked mole-rat(101724891) mannosidase, alpha, class 1B, member 1
  • Zebrafish(556237) mannosidase, alpha, class 1B, member 1
  • cow(100336900) mannosidase, alpha, class 1B, member 1
  • Horse(100147680) mannosidase, alpha, class 1B, member 1
  • dog(480667) mannosidase, alpha, class 1B, member 1
  • chicken(417296) mannosidase, alpha, class 1B, member 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MAN1B1 Antibody, clone 1D6, clone 1D6, from mouse,
Reactividad de especies
human, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-MAN1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-MAN1B1 antibody produced in mouse, clone 6B1, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
mouse
Aplicación
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Kifunensine, mannosidase inhibitor,
Especie
human, mouse, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Man1b1,
Especie
mouse
MISSION® esiRNA, targeting human MAN1B1,
Especie
human