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Merck

KCNN1

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

Sinónimos:
KCa2.1, SK1, SKCA1, hSK1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3780) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
  • Mouse(84036) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • Rat(54261) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic guinea pig(100715012) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • naked mole-rat(101717556) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • sheep(101112056) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • dog(484829) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • cow(408008) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic cat(101085608) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Apamin, from bee venom, ≥95% (HPLC),
Especie
rat
Apamin, synthetic, ≥97% (HPLC),
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KCNN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-KCNN1 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human KCNN1,
Especie
human