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Merck

HRAS

Harvey rat sarcoma viral oncogene homolog

Sinónimos:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Especie:
Human HRAS (3265), Rat Hras (293621), chicken HRAS (396229), dog HRAS (403735), cow HRAS (100298939), sheep HRAS (101104357), domestic guinea pig Hras (100735038), naked mole-rat Hras (101716053)
ID UniProtKB:
P01112, B5BUA0, Q14080, Q6FHV9, Q9BR65, Q9UCE2
ID del gen:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
G8877
Guanosina 5′-trifosfato sodium salt hydrate, ≥95% (HPLC), powder,
Especie
human
I0879
Inosine 5′-triphosphate trisodium salt, ≥95%,
Especie
human
G3776
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Especie
human
D7409
2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt, ≥90% (HPLC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4700841
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
Reactividad de especies
human
Aplicación
western blot
OP23
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
Reactividad de especies
human, mouse, rat
Aplicación
SAB4501441
Anti-RASH antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
ZRB1850
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
affinity binding assay
western blot
SAB4301113
Anti-RAS antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU134211
MISSION® esiRNA, targeting human HRAS,
Especie
human