CTSB
cathepsin B
Sinónimos:
APPS, CPSB
Especie:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), chicken CTSB (396329), dog CTSB (486077), domestic cat CTSB (101084873), cow CTSB (281105), Horse CTSB (100060963), sheep CTSB (780470), naked mole-rat Ctsb (101709008)
ID UniProtKB:
ID del gen:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- chicken(396329) cathepsin B
- dog(486077) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- Horse(100060963) cathepsin B
- sheep(780470) cathepsin B
- naked mole-rat(101709008) cathepsin B
- domestic guinea pig(100714169) cathepsin B
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reactividad de especies
bovine, human, porcine
Aplicación
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti- Cathepsin B antibody produced in mouse, clone CB59-4B11, purified from hybridoma cell culture,
Reactividad de especies
human, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Especie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
esiRNA
Small Molecule - Substrate
Referencia del producto
Descripción
Especie