CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
Sinónimos:
Especie:
Human CHRNA2 (1135), Mouse Chrna2 (110902), Rat Chrna2 (170945), chicken CHRNA2 (395607), cow CHRNA2 (531838), domestic cat CHRNA2 (101092104), dog CHRNA2 (486101), sheep CHRNA2 (101107330), domestic guinea pig Chrna2 (100734964), naked mole-rat Chrna2 (101714975)
ID UniProtKB:
ID del gen:
- Human(1135) Summary: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
- Mouse(110902) cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
- Rat(170945) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- chicken(395607) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- cow(531838) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic cat(101092104) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- dog(486101) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- sheep(101107330) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic guinea pig(100734964) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- naked mole-rat(101714975) cholinergic receptor, nicotinic, alpha 2 (neuronal)
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Small Molecule - Agonist
Referencia del producto
Descripción
Especie
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Especie
human, mouse, rat
Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Especie
human, mouse, rat
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CHRNA2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-CHRNA2 Antibody, clone 5B2.1, clone 5B2.1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-Chrna2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Small Molecule - Blocker
Small Molecule - Inhibitor
Small Molecule - Ligand
esiRNA
Referencia del producto
Descripción
Especie