ACLY
ATP citrate lyase
Sinónimos:
ACL, ATPCL, CLATP
Especie:
Human ACLY (47), Mouse Acly (104112), Rat Acly (24159), chicken ACLY (395373), Horse ACLY (100053195), cow ACLY (511135), domestic cat ACLY (100422779), dog ACLY (607852), naked mole-rat Acly (101700349), domestic guinea pig Acly (100714933)
ID UniProtKB:
ID del gen:
- Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(104112) ATP citrate lyase
- Rat(24159) ATP citrate lyase
- chicken(395373) ATP citrate lyase
- Horse(100053195) ATP citrate lyase
- cow(511135) ATP citrate lyase
- domestic cat(100422779) ATP citrate lyase
- dog(607852) ATP citrate lyase
- naked mole-rat(101700349) ATP citrate lyase
- domestic guinea pig(100714933) ATP citrate lyase
- sheep(654404) ATP citrate lyase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ACLY, clone 5F8D11 Antibody, clone 5F8D11, from mouse,
Reactividad de especies
human, monkey, mouse
Aplicación
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ATP-citrate synthase/ACLY Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse, porcine, rat, sheep
Aplicación
immunohistochemistry
western blot
western blot
Anti-ACLY Antibody, clone 1B16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Phospho-ACLY-S455 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Referencia del producto
Descripción
Especie
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Especie
human