Skip to Content
Merck
All Photos(1)

Key Documents

SRP0393

Sigma-Aldrich

EZH2/SUZ12/RbAp48 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥88% (SDS-PAGE)

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥88% (SDS-PAGE)

form

aqueous solution

mol wt

114 kDa (EZH2)
48 kDa (RbAP48)
87 kDa (SUZ12)

packaging

pkg of 20 μg

shipped in

dry ice

storage temp.

−70°C

Gene Information

General description

Complex of human EZH2 (GenBank Accession No. NM_004456) amino acids 2-end with N-terminal His-GST tag, MW= 114kDa; human SUZ12 (GenBank Accession No. NM_015355) amino acids 1-end with N-terminal His-tag, MW = 87kDa, and human RbAp48 (GenBank Accession No. NM_005610) amino acids 2-end with N-terminal His-tag, MW= 48 kDa, co-expressed in Baculovirus expression system.

Physical form

Formulated in 40 mM Tris-HCl, pH 8.0, 110mM NaCl, 2.2 mM KCl, 18 mM Glutathione, 3mM DTT, and 20% glycerol.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rakotobe, D. et al.
Journal of Virology, 5, 32-32 (2008)
Sooryanarayana Varambally et al.
Science (New York, N.Y.), 322(5908), 1695-1699 (2008-11-15)
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of target genes and regulates the survival and metastasis of cancer cells. EZH2 is overexpressed in aggressive solid tumors by mechanisms that remain

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service