SML3309
DN01
≥98% (HPLC)
Synonym(s):
4-(4-((Dimethylamino)methyl)-2,6-dimethoxyphenyl)-7-fluoro-2-methylisoquinolin-1(2H)-one
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About This Item
Empirical Formula (Hill Notation):
C21H23FN2O3
CAS Number:
Molecular Weight:
370.42
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
, White to light brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
DN01 is a potent and selective BRD8 first bromodomain inhibitor (BRD8(1) IC50 = 12 nM; BRD4(1) & BRD9 IC50 ≥10 μM) that serves as a useful chemical probe for the selective engagement of BRD8 and enrichment of native NuA4 complexes.
Potent and selective BRD8 first bromodomain inhibitor for probing the engagement of BRD8 and enrichment of native NuA4 complexes.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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