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SAB4700247

Sigma-Aldrich

Monoclonal Anti-CD21-PE antibody produced in mouse

clone LT21, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CR2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.44

biological source

mouse

conjugate

phycoerythrin (R-PE) conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

LT21, monoclonal

form

buffered aqueous solution

species reactivity

pig, human, bovine

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_001006658.2

UniProt accession no.

P20023

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CR2(1380)

General description

The antibody LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.

Immunogen

IM9 human B-lymphoblastoid cell line

Application

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Features and Benefits

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Physical form

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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M Faldyna et al.
Veterinary immunology and immunopathology, 119(1-2), 56-62 (2007-08-04)
We have characterized a panel of commercially available anti-human monoclonal antibodies (mAbs) suitable for B-cell identification in pigs and dogs. The specificities of the mAbs were against CD20, CD21, CD22, and CD86. In addition to HM57, originally raised against human

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