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Key Documents

P3531

Sigma-Aldrich

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine

≥99%

Synonym(s):

1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, 1,2-distearoyl, L-β,γ-Distearoyl-α-cephalin

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About This Item

Empirical Formula (Hill Notation):
C41H82NO8P
CAS Number:
Molecular Weight:
748.07
Beilstein:
1730641
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.77

Assay

≥99%

form

powder

lipid type

phospholipids

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1

InChI key

LVNGJLRDBYCPGB-LDLOPFEMSA-N

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Application


  • Injectable Composite Hydrogels Embedded with Gallium-Based Liquid Metal Particles for Solid Breast Cancer Treatment via Chemo-Photothermal Combination.: This article presents the use of DSPE in developing injectable composite hydrogels. These hydrogels are embedded with liquid metal particles to provide a dual-mode treatment approach combining chemotherapy and photothermal therapy for breast cancer (Lee et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elisabeth Mamelle et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 274(2), 729-736 (2016-10-08)
Goals of cochlear implantation have shifted from complete insertion of the cochlear electrode array towards low traumatic insertion with minimally invasive techniques. The aim of this study was first to evaluate, in a guinea pig model of cochlear implantation, the
Ting Zhang et al.
International journal of pharmaceutics, 515(1-2), 449-459 (2016-11-05)
Polysialic acid (PSA) serves as a hydrophilic polymer and affords conjugated biologically active molecules a longer circulation time in vivo. Furthermore, PSA could potentially target tumor tissues and help achieve better curative effects. In this study, PSA was conjugated with
Yi-Ping Fang et al.
International journal of nanomedicine, 13, 2789-2802 (2018-05-23)
SN38 (7-ethyl-10-hydroxycamptothecin) is a camptothecin derivative acts against various tumors. However, SN38 is hydrolyzed in the physiological environment (pH 7.4), and this instability interferes with its potential therapeutic effect. Our objective was to investigate SN38-loaded liposomes to overcome the poor
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ACS nano, 12(8), 7583-7600 (2018-07-14)
Nanomedicine drug delivery systems are capable of transporting significant payloads to solid tumors. However, only a modest increase in antitumor efficacy relative to the standard of care has been observed. In this study, we demonstrate that a single dose of
Ching-Hsiang Fan et al.
ACS synthetic biology, 6(11), 2021-2027 (2017-09-26)
We developed an ultrasound-chemical hybrid tool to precisely manipulate cellular activities. A focused ultrasound coupled with gas-filled microbubbles was used to rapidly trigger the influx of membrane-impermeable chemical dimerizers into living cells to regulate protein dimerization and location without inducing

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