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OLIGO

Custom DNA Oligos

Design and Order Custom Oligos

Synonym(s):

Custom DNA Oligos, DNA, DNA primer, High-throughput DNA, ISO 13485 Oligos, Locked Nucleic Acid oligos, Modified oligos, NGS adapters, NGS−grade oligos, Next−generation sequencing adapters, Next−generation sequencing oligos, Oligonucleotide, Oligonucleotides, Oligos, Oligos in plates, cGMP Oligos

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UNSPSC Code:
41105327

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Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
Eun Jung Thak et al.
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
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Custom DNA Oligos Modifications

We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.

Long Oligos

Our experience with gene construction and microarray development provides us with insight into the potential difficulties of long oligo synthesis. We have developed techniques to purify long oligos, which are unmatched by other suppliers.

Predesigned siRNA

We offer advanced design and quality synthesis for predesigned siRNA and siRNA libraries using the Rosetta siRNA Design Algorithm to reduce off-target effects and increase RNAi performance. The algorithm utilizes Position-Specific Scoring Matrices (PSSM) and knowledge of the siRNA seed region to predict the most effective and specific siRNA sequences for a target gene of interest.

Molecular Beacons

Molecular Beacons are structured probes that are highly sensitive, sequence specific, and are used for sequence detection in qPCR and in vitro studies.

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Oligonucleotide Label Licenses

Label licenses for our oligonucleotide products, including Black Hole Quencher®, BlackBerry® Quencher, and Locked Nucleic Acid (LNA®).

Oligonucleotide Quality Assurance: Quality Management System Components

Key components of our QMS (quality management system) include: certificates of analysis; document control; change notification; vendor management; business agreements; and, corrective and preventive actions.

No Template Control Oligos (NTCO)

If laboratory handling error has been ruled out, contaminated primers and probes may be to blame for a signal from the qPCR no template control.

Custom Oligo Blanket Orders

Custom oligo Blanket Purchase Order tracking system simplifies expenditure management for customers.

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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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