M3895
Mucin from bovine submaxillary glands
Type I-S
Synonym(s):
MUC
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About This Item
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biological source
bovine submaxillary glands
Quality Level
type
Type I-S
form
powder
composition
Bound sialic acids, 9-24%
technique(s)
electrophoresis: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... BSM(286841)
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General description
Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats.
Application
Mucin from bovine submaxillary glands has been used:
- in the quantification of mucin
- as a component of artificial tear solution
- as a substrate for recombinant sialidase Gardnerella vaginalis
- to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
- to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)
Biochem/physiol Actions
Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin.
Albuminoid substance in mucus which gives it its ropy consistency
Linkage
Similar to M 4503, but produced by Sigma.
Substrates
Neuraminidase substrate.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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