CLS3464
Corning® Costar® Transwell® cell culture inserts
TC treated, PET membrane, diam. 6.5 mm, pore size 8.0 μm, sterile
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About This Item
UNSPSC Code:
41122107
NACRES:
NB.13
Recommended Products
material
PET membrane
clear plate
flat bottom clear polystyrene wells
round wells
sterility
sterile
feature
lid
skirt
packaging
pack of 12 ea
case of 48 ea
manufacturer/tradename
Corning 3464
diam.
6.5 mm
membrane thickness × diam.
10 μm × 6.5 mm
size
24 wells
well working volume
0.6 mL
color
clear
pore size
8 μm
8.0 μm
binding type
Tissue Culture (TC)-treated surface
Related Categories
General description
The Transwell® cell culture inserts feature a distinctive self-centered and hanging design that effectively prevents the unwanted wicking of medium between the insert and outer well. This in turn ensures the uninterrupted and intact co-culturing of cells in the lower compartment, allowing for undisturbed cell growth and maintenance.
Application
The Corning® Costar® Transwell® cell culture inserts are well-suited for cell staining applications and various chemotaxis assays, including fibroblast migration studies, tumor invasion and metastasis, trans-migrational studies, and invasion inhibition research. The inserts have been used in:
- Transwell assay to study the role of TGF-β-MTA1-SMAD7-SMAD3-SOX4-EZH2 signaling axis in hepatocellular carcinoma cells
- MTT Assay to study GAS5-mediated signaling in osteosarcoma cells
- tri-cultured neuroinflammation model
Features and Benefits
- 10 μm thick transparent polyester membrane
- Treated for optimal cell attachment
- Sterilized by gamma radiation Lids included TC-treated surface 0.33 cm2 cell growth area
- Can be coated with a diverse range of extracellular matrices (ECM) and basement membrane extracts (BME)
- Optical clarity enables clear visualization of cell outlines when observed under phase contrast microscopy
- Offers compatibility with histochemical stains and fluorochromes for various cell staining applications
Legal Information
Corning is a registered trademark of Corning, Inc.
Costar is a registered trademark of Corning, Inc.
Transwell is a registered trademark of Corning, Inc.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Rodrigo Berzaghi et al.
Cancers, 11(5) (2019-05-22)
The abilities of cancer-associated fibroblasts (CAFs) to regulate immune responses in the context of radiotherapy remain largely unknown. This study was undertaken to determine whether ionizing radiation alters the CAF-mediated immunoregulatory effects on macrophages. CAFs were isolated from freshly-resected non-small
Yuan He et al.
American journal of physiology. Heart and circulatory physiology, 316(1), H233-H244 (2018-11-10)
Stem cell therapy is a potentially effective and promising treatment for ischemic heart disease. Resistin, a type of adipokine, has been found to bind to adipose-derived mesenchymal stem cells (ADSCs). However, the effects of resistin on cardiac homing by ADSCs
Aritro Nath et al.
Molecular cancer research : MCR, 19(2), 240-248 (2020-10-28)
Elevated uptake of saturated fatty acid palmitate is associated with metastatic progression of cancer cells; however, the precise signaling mechanism behind the phenomenon is unclear. The loss of cell adhesion proteins, such as desmoplakin (DSP), is a key driving event
Xinliang Zhang et al.
International journal of biological sciences, 15(7), 1460-1471 (2019-07-25)
Growth Arrest Specific 5 (GAS5), a long noncoding RNA (lncRNA), functions as a tumor suppressor in multiple cancers. However, its function, downstream targets and upstream regulatory mechanism are still obscure in osteosarcoma cells. Here, we discovered that GAS5 was downregulated
A Islam et al.
European cells & materials, 37, 153-174 (2019-02-21)
Mesenchymal stromal cells (MSCs), given their regenerative potential, are being investigated as a potential therapeutic tool for cartilage lesions. MSCs express several bioactive molecules which act in a paracrine fashion to modulate the tissue microenvironment. Yet, little is known about
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