A2661
Acetylcholine chloride
suitable for cell culture
Synonym(s):
ACh
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
(CH3)3N+CH2CH2OCOCH3Cl-
CAS Number:
Molecular Weight:
181.66
Beilstein:
3571875
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32190102
PubChem Substance ID:
NACRES:
NA.75
biological source:
synthetic
form:
powder
Assay:
~99%
Recommended Products
biological source
synthetic
Quality Level
Assay
~99%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
146-150 °C (lit.)
solubility
water: 100 mg/mL, clear, colorless
shipped in
ambient
storage temp.
room temp
SMILES string
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
JUGOREOARAHOCO-UHFFFAOYSA-M
Gene Information
human ... CHRM3(1131)
Looking for similar products? Visit Product Comparison Guide
Application
Acetylcholine chloride has been used in the preparation of acetylcholine, that is used as a common vehicle for iontophoresis of acetylcholine (ACh). It has also been used to treat aNS-1 derived neurons for cAMP (cyclic adenosine monophosphate) assay and also used to check their ability to influence G protein-coupled receptors (GPCRs).
Biochem/physiol Actions
Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
A novel gel based vehicle for the delivery of acetylcholine in quantitative sudomotor axon reflex testing
Sletten D M, et al.
Autonomic Neuroscience : Basic & Clinical, 150(1-2), 127-130 (2009)
Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates
Garavaglia A, et al.
BMC Neuroscience, 11(1), 7-7 (2010)
Yue-Chen Chang et al.
Kidney & blood pressure research, 43(5), 1607-1622 (2018-10-23)
This experimental study aims to observe whether the protective effect of propofol against renal ischemia-reperfusion injury (IRI) in the rat interlobar artery occurs through altered expression of the gap junction protein connexin 43 (Cx43). This study randomly divided male Sprague
Tracey Huynh et al.
Journal of medicinal chemistry, 56(20), 8196-8200 (2013-10-01)
The M4 mAChR is implicated in several CNS disorders and possesses an allosteric binding site for which ligands modulating the affinity and/or efficacy of ACh may be exploited for selective receptor targeting. We report the synthesis of a focused library
Elim Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(52), 21171-21176 (2013-12-12)
The habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain. In larval zebrafish, the bilaterally paired dorsal habenular nuclei (dHb) exhibit prominent left-right differences in their organization, gene expression
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service