44213

Thromboplastin from rabbit

• Synonym(s): Thromboplastin, Factor III, Thrombokinase
• CAS Number: 72162-96-0
• EC Number: 276-433-6
• MDL number: MFCD00148638
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• biological source: rabbit
• Quality Level: 100
• form: lyophilized solid
• UniProt accession no.: P24055
• storage temp.: 2-8°C
• Gene Information: rabbit ... F3(100009127)

Description

Application

Thromboplastin from rabbit has been used:

• as a standard in tissue factor procoagulant activity assay (TF-PCA)
• in pulmonary embolism assay
• as a positive control in clotting assay using human plasma

Biochem/physiol Actions

Thromboplastin (Tissue factor) is a transmembrane protein, the chief in vivo activator of blood coagulation that leads to thrombin generation and fibrin deposition. It is also important in the activation of the coagulation protease cascade and is involved in the lethality of sepsis.,

Thromboplastin from rabbit might be used to produce disseminated intravascular coagulation (DIC) in animal models.

Packaging

One vial contains 3-4 mg thromboplastin.

Reconstitution

Reconstitute the content of 1 vial in 4 ml 10 mm CaCl₂

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H334
• Precautionary Statements: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves