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MOPS

EMPROVE® EVOLVE

Pharma Manufacturing

Synonym(s):

MOPS, 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H15NO4S
CAS Number:
Molecular Weight:
209.26
Beilstein:
1106776
MDL number:
UNSPSC Code:
12161700

biological source

synthetic

Quality Level

product line

EMPROVE® EVOLVE

Assay

99.5%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

pH

2.5-4 (1 M in water)

useful pH range

6.5-7.9
6.5-7.9

pKa (25 °C)

7.2

pKa 

7.2

λ

1 M in water

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

storage temp.

2-30°C

SMILES string

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

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Application

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Packaging

100 g in poly bottle
1 kg in poly bottle
10, 25 kg in poly drum

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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