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Key Documents

P4894

Sigma-Aldrich

Poloxamer 188 PRO

solid, suitable for cell culture

Synonym(s):

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), PEG-PPG-PEG

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25

vapor density

>1 (vs air)

Quality Level

vapor pressure

<0.3 mmHg ( 20 °C)

form

solid
waxy solid

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/g Endotoxin

color

white to off-white

pH

5.0-7.5

solubility

H2O: soluble 100 g/L, clear, colorless to almost colorless

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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General description

Poloxamer 188 PRO has been specifically designed for use in cell culture, to improve cell viability and protect cells in suspension against possible damage during subculture, freezing and thawing, and stirring.

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.
Poloxamers are polymers often used for drug delivery as formulation exipients. Other applications include use as surfactants, emulsifying agents, solubilizing reagent, dispersing agents, gel binders, thickening agents, and as in vivo absorbance enhancers.

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.
Consistent quality - With our in-house developed methods we are able to predict the performance and ensure lot-to-lot consistency.
Superior performance - Our product performs superior to lots across different suppliers, batches and quality grades.
Reliable supply - Large manufacturing capacities ensure reliable supply for our customers.

Packaging

500 g in poly bottle

Physical form

Terminal primary dihydroxy-functional oligomer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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