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D9516

Supelco

Diaveridine

analytical standard, ≥99.0% (TLC)

Synonym(s):

5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O2
CAS Number:
5355-16-8
Molecular Weight:
260.29
Beilstein:
258464
EC Number:
226-333-3
MDL number:
MFCD00057349
UNSPSC Code:
41116107
PubChem Substance ID:
329798904
NACRES:
NA.24

grade

analytical standard

Quality Level

200

Assay

≥99.0% (TLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(Cc2cnc(N)nc2N)cc1OC

InChI

1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)

InChI key

LDBTVAXGKYIFHO-UHFFFAOYSA-N

Gene Information

rat ... Dhfr(24312)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCD2225
SLBT6641
SLBR2551V
SLBM1914V
SLBD3870V

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Sigma-Aldrich

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P D Walzer et al.
Antimicrobial agents and chemotherapy, 32(1), 96-103 (1988-01-01)
Inhibitors of folic acid synthesis were compared alone and in different combinations in the therapy of pneumocystosis in immunosuppressed rats. Sulfonamides (sulfamethoxazole, sulfadiazine, and sulfadoxine) and sulfones (dapsone) used alone were very active against Pneumocystis carinii, as judged by histologic
H Yoshimura
Mutation research, 261(2), 149-152 (1991-10-01)
The coccidiostat diaveridine was tested for mutagenicity in the Salmonella/microsome assay with tester strains TA100 and TA98. This compound was not mutagenic in either tester strain in the presence and absence of rat S9 mix, but was found to be
G Gigler et al.
Agents and actions. Supplements, 32, 39-43 (1991-01-01)
The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin
Zhao-Ying Liu et al.
Biomedical chromatography : BMC, 26(9), 1101-1108 (2011-12-14)
Trimethoprim (TMP) and diaveridine (DVD) are used in combination with sulfonamides and sulfaquinoxlaine as an effective antibacterial agent and antiprotozoal agent, respectively, in humans and animals. To gain a better understanding of the metabolism of TMP and DVD in the
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