D186309

Dimethyl sulfate

≥99.5%

• Synonym(s): Sulfuric acid dimethyl ester
• Linear Formula: (CH₃O)₂SO₂
• CAS Number: 77-78-1
• Molecular Weight: 126.13
• Beilstein: 635994
• EC Number: 201-058-1
• MDL number: MFCD00008416
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654074
• NACRES: NA.21

Properties

• vapor density: 4.3 (vs air)
• Quality Level: 200
• vapor pressure: 0.7 mmHg ( 25 °C)
• Assay: ≥99.5%
• form: liquid
• autoignition temp.: 923 °F
• refractive index: n20/D 1.386 (lit.)
• bp: 188 °C (lit.)
• mp: −32 °C (lit.)
• density: 1.333 g/mL at 25 °C (lit.)
• SMILES string: COS(=O)(=O)OC
• InChI: 1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3
• InChI key: VAYGXNSJCAHWJZ-UHFFFAOYSA-N

Description

Application

Dimethyl sulfate may be used along with alumina for preparation of monomethylated derivatives of alcohols, phenols and carboxylic acids. It may also be used in combination with dimethylformamide (DMF) to form methoxy-methylene-N,N-dimethyliminium salt, that can be utilized for the preparation of β-lactams.

Packaging

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18 L in Kilo-Lab^® packaging not available in all areas.

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Legal Information

Kilo-Lab is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314,H317,H330,H341,H350
• Precautionary Statements: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 181.4 °F - closed cup
• Flash Point(C): 83 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves