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33975

Supelco

Carprofen

VETRANAL®, analytical standard

Synonym(s):

6-Chloro-α-methyl-9H-carbazole-2-acetic acid

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About This Item

Empirical Formula (Hill Notation):
C15H12ClNO2
CAS Number:
53716-49-7
Molecular Weight:
273.71
EC Number:
258-712-4
MDL number:
MFCD00079028
UNSPSC Code:
41116107
PubChem Substance ID:
329754715
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

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General description

Carprofen, is a non-steroidal anti-inflammatory drug, generally used to treat degenerative joint disease like canine osteoarthritis in animals. It can also be used like an analgesic agent to control the postoperative pain produced, during ovariohysterectomy in cats.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD4355
BCBZ6161
SZBE090XV
SZBB102XV
SZB9140XV

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Angelo D Favia et al.
Journal of medicinal chemistry, 55(20), 8807-8826 (2012-10-10)
Pain and inflammation are major therapeutic areas for drug discovery. Current drugs for these pathologies have limited efficacy, however, and often cause a number of unwanted side effects. In the present study, we identify the nonsteroidal anti-inflammatory drug carprofen as
Laura Bertolacci et al.
Journal of the American Chemical Society, 135(1), 22-25 (2012-12-18)
In addition to inhibiting the cyclooxygenase (COX)-mediated biosynthesis of prostanoids, various widely used nonsteroidal anti-inflammatory drugs (NSAIDs) enhance endocannabinoid signaling by blocking the anandamide-degrading membrane enzyme fatty acid amide hydrolase (FAAH). The X-ray structure of FAAH in complex with the
I N Plessas et al.
The Veterinary record, 171(20), 501-501 (2012-10-27)
The disease complex Chiari-like malformation (CM) and syringomyelia (SM) has been associated with the development of neuropathic pain (NeP), and commonly affects Cavalier King Charles spaniels (CKCS). This prospective cohort study followed 48 CKCSs with CM and/or SM and clinical
D C Brown et al.
Journal of veterinary internal medicine, 27(1), 22-30 (2013-01-15)
Lameness assessment using force plate gait analysis (FPGA) and owner assessment of chronic pain using the Canine Brief Pain Inventory (CBPI) are valid and reliable methods of evaluating canine osteoarthritis. There are no studies comparing these 2 outcome measures. Evaluate
Postoperative analgesia in the cat after ovariohysterectomy by use of carprofen, ketoprofen, meloxicam or tolfenamic acid
Slingsby.S.L and Waterman-Peterson.E.A
The Journal of Small Animal Practice, 41, 447-450 (2000)
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