AB9884
Anti-Clathrin Light Chain Antibody
serum, Chemicon®
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CLTA(1211)
Specificity
Clathrin light chain a and b variants (CLC). By Western blot the antibody recognizes a doublet at ~35-40 kDa on rat brain extracts.
Application
This Anti-Clathrin Light Chain Antibody is validated for use in WB for the detection of Clathrin Light Chain.
Western blot: 1:50,000-1:100,000 on rat brain extracts.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Target description
~35-40 kDa
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Fan Fan et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(32) (2021-08-08)
Pancreatic β cells operate with a high rate of membrane recycling for insulin secretion, yet endocytosis in these cells is not fully understood. We investigate this process in mature mouse β cells by genetically deleting dynamin GTPase, the membrane fission
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.
Zlatic, SA; Grossniklaus, EJ; Ryder, PV; Salazar, G; Mattheyses, AL; Peden, AA; Faundez, V
Molecular Biology of the Cell null
Patrick D Allaire et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26(51), 13202-13212 (2006-12-22)
Clathrin-coated vesicles (CCVs) are responsible for the endocytosis of multiple cargo, including synaptic vesicle membranes. We now describe a new CCV protein, termed connecdenn, that contains an N-terminal DENN (differentially expressed in neoplastic versus normal cells) domain, a poorly characterized
Kazuki Obashi et al.
Nature communications, 14(1), 732-732 (2023-02-10)
Conformational changes in endocytic proteins are regulators of clathrin-mediated endocytosis. Three clathrin heavy chains associated with clathrin light chains (CLC) assemble into triskelia that link into a geometric lattice that curves to drive endocytosis. Structural changes in CLC have been
Mian Cao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(49), 16544-16549 (2014-12-05)
Several proteins encoded by PD genes are implicated in synaptic vesicle traffic. Endophilin, a key factor in the endocytosis of synaptic vesicles, was shown to bind to, and be ubiquitinated by, the PD-linked E3 ubiquitin ligase Parkin. Here we report
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