I-009

Ibuprofen solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₃H₁₇O₂
• CAS Number: 15687-27-1
• Molecular Weight: 205.27
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: CC(C)Cc1ccc(cc1)C(C)C([O-])=O
• InChI: 1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/p-1
• InChI key: HEFNNWSXXWATRW-UHFFFAOYSA-M

Description

General description

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation. Ibuprofen functions as an unspecific COX inhibitor. This Certified Spiking Solution^® is applicable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or pharmaceutical research.

Application

• Ibuprofen solution in environmental analysis: A study demonstrated the use of green and efficient magnetic micro-solid phase extraction techniques, utilizing tea waste impregnated with magnetic nanoparticles for the analysis of ibuprofen in water samples. This method, enhanced by UV-vis spectrophotometry, showcases the application of ibuprofen solution in monitoring pharmaceutical pollutants, ensuring environmental safety and compliance (Muniandy et al., 2024).


• Pharmacological research with ibuprofen solution: Research into less toxic solvents for in-situ forming PLGA implants incorporated ibuprofen solutions to study drug release profiles. This investigation highlights the role of ibuprofen solution in developing advanced drug delivery systems that are crucial for controlled and sustained medication release, enhancing patient compliance and therapeutic outcomes (Ramos et al., 2024).


• Ibuprofen solution in biomedical applications: A novel study utilized ibuprofen solution to fabricate a green electrospun Janus membrane doped with hierarchical magnesium hydrogen phosphate. This research underlines the utility of ibuprofen in creating advanced materials for the removal of pharmaceuticals from water, contributing to the development of new filtration technologies (Zhu et al., 2024).


• Ibuprofen solution in neuroscience: Researchers quantified the lymphatic transport of model therapeutics from the brain using ibuprofen solutions in rats. This study provides valuable insights into the mechanisms of drug transport in neurological conditions, offering potential pathways for targeted drug delivery to the brain (Hoang et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H301 + H311 + H331 - H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup