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Key Documents

ALD00626

Sigma-Aldrich

6-(2-(Quinolin-2-yl)propan-2-yl)pyridin-2-ol

≥95%

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About This Item

Empirical Formula (Hill Notation):
C17H16N2O
Molecular Weight:
264.32

Quality Level

Assay

≥95%

form

powder

mp

181-185 °C

storage temp.

−20°C

Application

This ligand was developed by the Yu lab to enable the Pd-catalyzed dehydrogenation of aliphatic carboxylic acids through a typically challenging activation of the β-methylene C-H bond. This method is chemoselective to carboxylic acids even in the presence of other enolizable functional groups, and may also viably utilize molecular oxygen as the terminal oxidant for the transformation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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