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931853

Sigma-Aldrich

SPhos Pd G6 acylation

greener alternative

≥95%

Synonym(s):

(SPhos)Pd(4-CH2CH2CONHSPh)Br

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About This Item

Empirical Formula (Hill Notation):
C39H47BrNO6PPd
CAS Number:
Molecular Weight:
843.09
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.21

Quality Level

Assay

≥95%

form

powder

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

greener alternative product characteristics

Catalysis
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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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