916080

Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

≥95%

• Synonym(s): 4-Alkyl-1,4-dihydropyridine reagent, DHP reagent for light-mediated His modification
• Empirical Formula (Hill Notation): C₁₉H₂₉NO₄
• CAS Number: 1539-59-9
• Molecular Weight: 335.44
• MDL number: MFCD01100492
• UNSPSC Code: 12352200

Properties

• Assay: ≥95%
• form: powder
• storage temp.: −20°C
• InChI: 1S/C19H29NO4/c1-5-23-18(21)15-12(3)20-13(4)16(19(22)24-6-2)17(15)14-10-8-7-9-11-14/h14,17,20H,5-11H2,1-4H3
• InChI key: GERWBKSVDHUVIT-UHFFFAOYSA-N

Description

Application

Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate was reported to chemoselectively modify histidine under visible light where the unsubstituted nitrogen groups on the modified His imidazole are conserved. Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate is also a versitile reagent for photoredox chemistry.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Histidine-specific peptide modification via visible-light-promoted C-H alkylation

Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis

A photocatalyst-free photo-induced denitroalkylation of ß-nitrostyrenes with 4-alkyl substituted Hantzsch esters at room temperature

Intermolecular Radical Addition to Ketoacids Enabled by Boron Activation

Oxa- and Azabenzonorbornadienes as Electrophilic Partners under Photoredox/Nickel Dual Catalysis

Exploration of a chiral cobalt catalyst for visible-light-induced enantioselective radical conjugate addition

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable