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798681

Sigma-Aldrich

Ethylenediaminetetraacetic acid

anhydrous, free-flowing, Redi-Dri™, ≥98%

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
60-00-4
Molecular Weight:
292.24
Beilstein:
1716295
EC Number:
200-449-4
MDL number:
MFCD00003541
UNSPSC Code:
12352100
PubChem Substance ID:
329768665
NACRES:
NA.21

Agency

suitable for SM 4500 - NH3

Quality Level

100

product line

Redi-Dri™

Assay

≥98%

form

powder

mp

250 °C (dec.) (lit.)

density

1.46 g/cm3 at 20 °C

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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Application


  • Enamel Matrix Derivative, 58S5 Bioactive Glass, and Fluoride Varnish for Enamel Remineralization: A Multi-analysis Approach.: This study explores the effectiveness of various agents including ethylenediaminetetraacetic acid (EDTA) in enamel remineralization processes, providing insights into dental applications of EDTA (Gungor et al., 2024).

  • Mathematical modeling of rare earth element separation in electrodialysis with adjacent anion exchange membranes and ethylenediaminetetraacetic acid as chelating agent.: This research investigates the use of EDTA as a chelating agent in the separation of rare earth elements, highlighting its industrial applications in electrodialysis processes (Ding and Azimi, 2024).

  • Comparative effects of 17% ethylenediaminetetraacetic acid and 9% etidronic acid applied with different irrigant activation techniques on the release of growth factors from dentin: in vitro study.: This paper examines the release of growth factors from dentin when treated with EDTA, contributing to the understanding of its role in dental health and regeneration (Mumcu et al., 2024).

  • EDTA functionalized pine needle biochar (EDTA@BC); a valorized bio-material for removal of Ni(II) from aqueous solution.: The study showcases the use of EDTA-functionalized biochar for the removal of heavy metals from water, emphasizing its significance in water treatment applications (Rasheed et al., 2024).

  • Impact of using XP-endo finisher and nanobubble water during EDTA dentin conditioning on TGF-beta1 release in regenerative endodontic procedures.: This research highlights the application of EDTA in enhancing the release of TGF-beta1, important for regenerative dental therapies (Hanafy et al., 2024).

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB8755
BCBZ4622
BCCB1428
BCBW2678
BCBV9310

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Jinqiang Liu et al.
Archives of oral biology, 118, 104843-104843 (2020-07-28)
The present purpose was to investigate the involvement of Derlin-3 in the endoplasmic reticulum stress pathway-mediated apoptosis of chondrocytes in biomechanically stimulated mandibular condylar cartilage. First, fluid flow shear stress (FFSS) was applied to ATDC5 cells with or without overexpression
Yi Wen et al.
Theranostics, 9(15), 4265-4286 (2019-07-10)
Periodontal ligament stem cells (PDLSCs) can repair alveolar bone defects in periodontitis in a microenvironment context-dependent manner. This study aimed to determine whether different extracellular matrices (ECMs) exert diverse effects on osteogenic differentiation of PDLSCs and accurately control alveolar bone
Haiyang Zhang et al.
Journal of tissue engineering and regenerative medicine, 13(6), 986-996 (2019-02-28)
Adipose tissue-derived stem cells (ADSCs) have shown effectiveness in treating diabetic bladder dysfunction (DBD). In the present study, ADSCs pretreated by defocused low-energy shock wave (DLSW) were first used to achieve better therapeutic effect. ADSCs were treated by DLSW prior
Purushothama Rao Tata et al.
Developmental cell, 44(6), 679-693 (2018-03-28)
We show that the loss or gain of transcription factor programs that govern embryonic cell-fate specification is associated with a form of tumor plasticity characterized by the acquisition of alternative cell fates normally characteristic of adjacent organs. In human non-small
Yang Yang et al.
Journal of the American Society of Nephrology : JASN, 29(9), 2310-2325 (2018-07-26)
Autosomal-dominant polycystic kidney disease (ADPKD) is the leading inherited renal disease worldwide. The proproliferative function of macrophages is associated with late-stage cyst enlargement in mice with PKD; however, the way in which macrophages act on cyst-lining epithelial cells (CLECs) has
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