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Key Documents

747068

Sigma-Aldrich

Poly(N-isopropylacrylamide), azide terminated

average Mn 15,000, PDI ≤1.4

Synonym(s):

Azide PolyNIPAM, PNIPAAm, PNIPAM-N3

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

Quality Level

mol wt

average Mn 15,000

PDI

≤1.4

storage temp.

2-8°C

Application

Poly(N-isopropylacrylamide) is a stimuli responsive polymer and synthesized by controlled radical polymerization to achieve a narrow polydispersity. The azide functionality is commonly used as a click group which can react with acetylene/alkyne groups. This polymer can be used to bind to proteins to form stable protein-polymer hybrids with responsive properties.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Macromolecular Rapid Communications, 29, 1172-1176 (2008)

Articles

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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