Skip to Content
Merck
All Photos(4)

Key Documents

More Documents

243086

Sigma-Aldrich

Pyridine hydrochloride

98%

Synonym(s):

Pyridinium chloride

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Empirical Formula (Hill Notation):
C5H5N · HCl
CAS Number:
628-13-7
Molecular Weight:
115.56
Beilstein:
3615340
EC Number:
211-027-4
MDL number:
MFCD00012802
UNSPSC Code:
12352100
eCl@ss:
39151701
PubChem Substance ID:
24854598
NACRES:
NA.22

Quality Level

200

Assay

98%

bp

222-224 °C (lit.)

mp

145-147 °C (lit.)

solubility

ethanol: soluble 50 mg/mL, clear, colorless to light yellow

SMILES string

Cl[H].c1ccncc1

InChI

1S/C5H5N.ClH/c1-2-4-6-5-3-1;/h1-5H;1H

InChI key

AOJFQRQNPXYVLM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Pyridine hydrochloride is an acidic type demethylating agent used as a catalyst in deprotection of aromatic methyl ethers.

Application

Pyridine hydrochloride (pyridine hydrochloride) was used in the demethylation of 4,5-dimethyl-7-methoxy-1-tetralone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 - H315 - H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Demethylation of methyl aryl ethers using pyridine hydrochloride in solvent-free conditions under microwave irradiation.
Kulkarni PP, et al.
J. Chem. Res. Synop., 6, 394-395 (1999)
Tatyana N Sevastyanova et al.
Molecular pharmacology, 86(5), 492-504 (2014-08-13)
Metabotropic glutamate receptors (mGluRs) function as dimers. Recent work suggests that mGluR1 and mGluR5 may physically interact, but the nature and functional consequences of this relationship have not been addressed. In this study, the functional and pharmacological consequences of this
Nathalie Ségaud et al.
Inorganic chemistry, 52(2), 691-700 (2013-01-11)
We report the synthesis, characterization, and solution chemistry of a series of new Fe(II) complexes based on the tetradentate ligand N-methyl-N,N'-bis(2-pyridyl-methyl)-1,2-diaminoethane or the pentadentate ones N,N',N'-tris(2-pyridyl-methyl)-1,2-diaminoethane and N,N',N'-tris(2-pyridyl-methyl)-1,3-diaminopropane, modified by propynyl or methoxyphenyltriazolyl groups on the amino functions. Six of
Jipan Yu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(13), 4271-4277 (2013-02-13)
Efficient copper-catalyzed aerobic oxidative C-H and C-C functionalization of 1-[2-(arylamino)aryl]ethanones leading to acridones has been developed. The procedure involves cleavage of aromatic C-H and acetyl C-C bonds with intramolecular formation of a diarylketone bond. The protocol uses inexpensive Cu(O2CCF3)2 as
Ye Wei et al.
Journal of the American Chemical Society, 135(10), 3756-3759 (2013-02-27)
We describe here a [3+3]-type condensation reaction of O-acetyl ketoximes and α,β-unsaturated aldehydes that is synergistically catalyzed by a copper(I) salt and a secondary ammonium salt (or amine). This redox-neutral reaction allows modular synthesis of a variety of substituted pyridines
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service