Skip to Content
Merck
All Photos(1)

Key Documents

SML3439

Sigma-Aldrich

IXA4

98% (HPLC)

Synonym(s):

N-​Methyl-​N-​[2-​(4-​methylphenoxy)​ethyl]​-​4-​[(1-​oxo-​3-​phenoxypropyl)​amino]​-1H-​pyrazole-​1-​acetamide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H28N4O4
CAS Number:
Molecular Weight:
436.50
MDL number:
UNSPSC Code:
12352200

Quality Level

Assay

98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(CN1N=CC(NC(CCOC2=CC=CC=C2)=O)=C1)N(C)CCOC3=CC=C(C=C3)C

Biochem/physiol Actions

IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service