S1172

Anti-Syntaxin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

• Synonym(s): Anti-GEFSP9, Anti-STX1B1, Anti-STX1B2
• MDL number: MFCD00164742
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse, rat
• technique(s): immunohistochemistry: suitable using rat brain sections; western blot (chemiluminescent): 1:1,000 using rat brain membranes
• UniProt accession no.: P61266
• storage temp.: −20°C
• Gene Information: mouse ... Stx1a(20907) , Stx1b(56216) ; rat ... Stx1a(116470) , Stx1b(24923)

Description

General description

Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.

Immunogen

highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).

Application

Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.

Biochem/physiol Actions

Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.

Physical form

After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H312 + H332 - H412
• Precautionary Statements: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves