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RAB0824

Sigma-Aldrich

Mouse Olr1 / Oxidized Low-density Lipoprotein Receptor 1 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.84

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Olr1(108078)

General description

The antibody pair provided in this kit recognizes mouse Oxidized Low-density Lipoprotein Receptor 1.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Oxidized low-density lipoprotein receptor 1 (OLR1), also referred as Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), acts as a scavenger receptor for oxidized low-density lipoprotein (ox-LDL). It is essential for formation and progression of atherosclerotic plaques. Therefore, mutation in the gene increases the risk of susceptibility to atherosclerotic-related diseases. In addition, genetic variation in the gene leads to myocardial infarction. Serum concentration of OLR1 serves as an efficient biomarker of intracerebral hemorrhage (ICH).

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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LOX-1 and atherosclerotic-related diseases.
Jin P and Cong S
Clinica Chimica Acta; International Journal of Clinical Chemistry, 491, 24-29 (2019)
Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction
Tatsuguchi M, et al.
Biochemical and Biophysical Research Communications, 303(1), 247-250 (2003)
Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage
Inoue T, et al.
Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association, 28(2), 490-494 (2019)
Akshay Sood et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(5), 459-466 (2014-01-23)
Adipose tissue produces adiponectin, an anti-inflammatory protein. High systemic total adiponectin is associated with a low risk for incident asthma but the association with lung adiponectin is not known. Our objective was to evaluate the association between sputum total adiponectin

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