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P6617

Sigma-Aldrich

Pristanic acid

≥97% (GC), ethanol solution

Synonym(s):

2,6,10,14-Tetramethylpentadecanoic acid

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About This Item

Empirical Formula (Hill Notation):
C19H38O2
CAS Number:
1189-37-3
Molecular Weight:
298.50
EC Number:
200-578-6
MDL number:
MFCD05664739
UNSPSC Code:
12352106
PubChem Substance ID:
329820250
NACRES:
NA.77

product name

Pristanic acid solution, mixture of isomers, ethanol solution, ≥97% (GC)

Quality Level

200

Assay

≥97% (GC)

form

ethanol solution

storage temp.

−20°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC(C)C(O)=O

InChI

1S/C19H38O2/c1-15(2)9-6-10-16(3)11-7-12-17(4)13-8-14-18(5)19(20)21/h15-18H,6-14H2,1-5H3,(H,20,21)

InChI key

PAHGJZDQXIOYTH-UHFFFAOYSA-N

Biochem/physiol Actions

Oxidation product of fatty acids in the diet, particularly phytanic acid. Phytanic acid is oxidized by alpha oxidation yielding pristanic acid, which is subsequently degraded by peroxisomal beta oxidation. Several inborn errors of metabolism with one or more deficiencies in the phytanic acid and pristanic acid breakdown have been described.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

55.4 °F

Flash Point(C)

13 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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James A Mobley et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12(8), 775-783 (2003-08-15)
An enzyme previously identified as alpha-methylacyl-CoA racemase (AMACR) is overexpressed in high-grade prostatic intraepithelial neoplasia and in a majority (60-100%) of prostate cancers (CaPs) as compared with normal and benign hyperplastic lesions of the prostate, where it is minimally expressed.
Biochemical markers predicting survival in peroxisome biogenesis disorders.
Jeannette Gootjes et al.
Advances in experimental medicine and biology, 544, 67-68 (2004-01-10)
J Gootjes et al.
Neurology, 59(11), 1746-1749 (2002-12-11)
To identify prognostic markers reflecting the extent of peroxisome dysfunction in primary skin fibroblasts from patients with peroxisome biogenesis disorders (PBD). PBD are a genetically heterogeneous group of disorders due to defects in at least 11 distinct genes. Zellweger syndrome
Phytanic and pristanic acid are naturally occuring ligands.
Anna W M Zomer et al.
Advances in experimental medicine and biology, 544, 247-254 (2004-01-10)
R J Wanders et al.
European journal of pediatrics, 153(7 Suppl 1), S44-S48 (1994-01-01)
Peroxisomal disorders represent a recently recognized group of inherited diseases in man, now comprising 14 different disorders. If discussion is restricted to those peroxisomal disorders in which there is neurological involvement (thereby excluding hyperoxaluria and acatalasaemia), results over the least
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