F5551
Hemagglutinin, Filamentous from Bordetella pertussis
lyophilized powder
Synonym(s):
Anti-HA, FHA, Hemagglutinin, Fimbrial
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General description
Filamentous Hemagglutinin (FHA) from Bordetella pertussis is a major virulence-associated adhesion factor secreted by these bacteria. It contains an arginine-glycine-aspartate (RGD) sequence. FHA is a derivative of its precursor FhaB.
Biochem/physiol Actions
Filamentous Hemagglutinin (FHA) from Bordetella pertussis enables the attachment of bacteria to the epithelium of the upper respiratory tract. The arginine-glycine-aspartate (RGD) sequence mediates the binding of FHA to sulfated polysaccharides and pulmonary macrophage integrins.
Physical form
lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Elizabeth M Goebel et al.
PloS one, 4(8), e6778-e6778 (2009-08-27)
Although B. bronchiseptica efficiently infects a wide range of mammalian hosts and efficiently spreads among them, it is rarely observed in humans. In contrast to the many other hosts of B. bronchiseptica, humans are host to the apparently specialized pathogen
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