C0158

L-Carnitine inner salt

synthetic, ≥98%

• Synonym(s): (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin B_T
• Linear Formula: (CH₃)₃N⁺CH₂CH(OH)CH₂COO^-
• CAS Number: 541-15-1
• Molecular Weight: 161.20
• Beilstein: 4292315
• EC Number: 208-768-0
• MDL number: MFCD00038747
• UNSPSC Code: 12352209
• PubChem Substance ID: 24892238
• NACRES: NA.79

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥98%
• form: powder
• color: white
• mp: 197-212 °C (lit.)
• application(s): cell analysis; detection
• SMILES string: C[N+](C)(C)C[C@H](O)CC([O-])=O
• InChI: 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
• InChI key: PHIQHXFUZVPYII-ZCFIWIBFSA-N

Description

Application

L-Carnitine inner salt has been used as a component of an assay medium for Seahorse XF mitochondrial stress assay. It has also been orally administered to tumor-bearing mice, in order to study its effect on the regulation of peroxisome proliferator-activated receptor and thereby to analyse liver inflammatory response.

Biochem/physiol Actions

Carnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment. In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branched chain amino acids.

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves