A4339
N-Acetyl-Tyr-Val-Lys(biotinyl)-Asp 2,6-dimethylbenzoyloxymethyl ketone
≥90% (HPLC), powder
Synonym(s):
Ac-YVK(biotinyl)D 2,6-dimethylbenzoyloxymethyl ketone
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About This Item
Empirical Formula (Hill Notation):
C46H63N7O12S
CAS Number:
Molecular Weight:
938.10
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.77
Application
Useful for affinity labeling the larger subunit of activated caspase 1 and caspase 1 related proteases.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Dodheri Syed Samiulla et al.
Organic and medicinal chemistry letters, 2(1), 27-27 (2012-07-17)
Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a therapeutic target has led many to pursue the development of inhibitors. To date, only a few series of non-peptide inhibitors
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