1.06535

Sodium nitrate

cryst. EMPLURA^®

• Synonym(s): Sodium nitrate, Nitric acid sodium salt
• Empirical Formula (Hill Notation): NNaO₃
• CAS Number: 7631-99-4
• Molecular Weight: 84.99
• UNSPSC Code: 12352302
• EC Index Number: 231-554-3

Properties

• Quality Level: 200
• product line: EMPLURA^®
• Assay: 99.0-100.5% dry basis (acidimetric)
• form: solid
• potency: 1267 mg/kg LD₅₀, oral (Rat)
• impurities: ≤0.2% Total chlorine
• loss: ≤2% loss on drying, 105°C
• pH: 5.5-8.0 (20 °C, 50 g/L in H₂O)
• mp: 308 °C
• solubility: 874 g/L
• density: 2.26 g/cm³ at 20 °C
• bulk density: 1200 kg/m³
• anion traces: nitrite (NO₂^-): ≤0.002%
• cation traces: As: ≤0.0003%; Fe: ≤0.001%; Hg: ≤0.0001%; K: ≤0.01%; Pb: ≤0.0002%; Zn: ≤0.001%
• storage temp.: 2-30°C
• InChI: 1S/NO3.Na/c2-1(3)4;/q-1;+1
• InChI key: VWDWKYIASSYTQR-UHFFFAOYSA-N

Description

Application

• Nitric oxide pros and cons: The role of L-arginine, a nitric oxide precursor, and idebenone, a coenzyme-Q analogue in ameliorating cerebral hypoxia in rat.: This study discusses the dual roles of nitric oxide and sodium nitrate′s contribution to ameliorating cerebral hypoxia, providing insights into its neurological applications (Abdel Baky NA et al., 2010).


• Use of experimental design methodology for the development of new magnetic siRNA nanovectors (MSN).: This study details the innovative application of sodium nitrate in the development of magnetic siRNA nanovectors, highlighting its role in enhancing delivery systems (David S et al., 2013).

Analysis Note

Assay (acidimetrisch, after drying): 99.0 - 100.5 %
Identity: passes test
pH-value (5 %; water): 5.5 - 8.3
Total chlorine: ≤ 0.2 %
Nitrite (NO₂): ≤ 0.002 %
As (Arsenic): ≤ 0.0003 %
Fe (Iron): ≤ 0.001 %
Hg (Mercury): ≤ 0.0001 %
K (Potassium): ≤ 0.01 %
Pb (Lead): ≤ 0.0002 %
Zn (Zinc): ≤ 0.001 %
Loss on Drying (105°C): ≤ 2.0 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS03,GHS07
• Signal Word: Warning
• Hazard Statements: H272 - H319
• Precautionary Statements: P210 - P220 - P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Ox. Sol. 3
• Storage Class Code: 5.1B - Oxidizing hazardous materials
• WGK: WGK 1
• Flash Point(F): does not flash
• Flash Point(C): does not flash