860403P

16:0-d31-18:1 PS

Avanti Polar Lipids 860403P, powder

• Synonym(s): 1-palmitoyl-d31-2-oleoyl-sn-glycero-3-[phospho-L-serine] (sodium salt)
• Empirical Formula (Hill Notation): C₄₀H₄₄NO₁₀PNaD₃₁
• CAS Number: 327178-96-1
• Molecular Weight: 815.18
• UNSPSC Code: 12352100
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (860403P-10mg); pkg of 1 × 25 mg (860403P-25mg)
• manufacturer/tradename: Avanti Polar Lipids 860403P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([
• InChI: 1S/C40H76NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,36-37H,3-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b18-17-;/t36-,37+;/m1./s1/i2D3,4D2,6D2,8D2,10D2,12D2,14D2,16D2,19D2,21D2,23D2,25D2,27D2,29D2,31D2;
• InChI key: RQYKXRYGZHMUSU-XETPNRLVSA-M

Description

General description

16:0-d31-18:1 PS is a deuterated phosphatidylserine (PS). This glycerophospholipid is also a natural phospholipid nutrient. Phosphatidylserine (PS) constitutes a major part of the cell membrane. It is present in the lungs, brain, liver, and skeletal muscle.

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

16:0-d31-18:1 PS may be used in the preparation of lipids substrates and to study the substrate specificity of endothelial lipase (EL) for polar head groups of the phospholipids. It may also be used as an internal standard for lipid extraction from human and murine tissue samples.

Biochem/physiol Actions

Phosphatidylserine (PS) regulates apoptosis and blood clotting. It maintains the activity of receptors, ion channels, enzymes and signaling molecules. PS also modulates membrane fluidity. It has ergogenic properties and suppresses muscle soreness in athletes.

Packaging

5 mL Clear Glass Sealed Ampule (860403P-10mg)

5 mL Clear Glass Sealed Ampule (860403P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids