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850373P

Avanti

24:0 PC

1,2-dilignoceroyl-sn-glycero-3-phosphocholine, powder

Synonym(s):

1,2-ditetracosanoyl-sn-glycero-3-phosphocholine; PC(24:0/24:0) ; 110929

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About This Item

Empirical Formula (Hill Notation):
C56H112NO8P
CAS Number:
91742-11-9
Molecular Weight:
958.46
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850373P-200mg)
pkg of 1 × 25 mg (850373P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850373P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[N+](C)(C)C)=O)(OC(CCCCCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCCCCC)=O

General description

24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) is a long-chain diacyl phospholipid. It consists of C24 saturated hydrocarbon chains.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) may be used:
  • in both short-chain micelles and longer-chain oriented multilayers and in Langmuir monolayers for structural studies of the human immunodeficiency virus 1 (HIV-1) accessory protein
  • to compare cohesion/to study the effects of lipid cohesion on the thermally induced revaporization and dissolution of microbubble condensed droplets (MCDs)
  • to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP) and to study the effects of the its carbon chain length on α-secretase activity

Biochem/physiol Actions

Phosphatidylcholines (PCs) serve as a major source for eicosanoids.

Packaging

5 mL Amber Glass Screw Cap Vial (850373P-200mg)
5 mL Amber Glass Screw Cap Vial (850373P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Paul A Mountford et al.
Langmuir : the ACS journal of surfaces and colloids, 31(16), 4627-4634 (2015-04-09)
This study explored the thermal conditions necessary for the vaporization of superheated perfluorocarbon nanodrops. Droplets C3F8 and C4F10 coated with a homologous series of saturated diacylphosphatidylcholines were formed by condensation of 4 μm diameter microbubbles. These drops were stable at
Marcus O W Grimm et al.
International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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